张磊博士

发布者:生物与农业资源学院办公室发布时间:2024-03-01浏览次数:103

    张磊,武汉大学医学博士。202010月至今任职生物与农业资源学院,讲师。研究方向为心血管疾病与基因多态性关系,及天然药物活性成分与心血管疾病防治。主持湖北省教育厅科技项目(B2021234),黄冈市科协智库项目(HGZK202206),黄冈市社科研究课题(2023年度087号),黄冈师范学院智库课题研究一项(202320304),黄冈师范学院2023年度重大项目培育计划202315304),湖北省重点实验室开放基金项目(202303302

近五年成果

1. Zhang L, Yang Z, Li X, Hua Y, Fan G, He F. Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation. BMC Complement Med Ther. 2023 Oct 25;23(1):378.

2. Zhang Lei, Lin Jingyi, Zhang Can, Hu Sijing, Dong Yang, Fan Guanwei and He Feng*, Recent Advances in the Nanotechnology-Based Applications of Essential Oils, Current Nanoscience 2024; 20 (5) .

3. Yimin Wang, Yanan Zhang, Zhihui Yang, Lei Zhang, Xiangping Chen, Guliang Yang,Jianfeng Zhan,Shiming Li,Feng He, & Guanwei Fan,  (2023). Mesoporous silica-based nanocarriers with dual response to pH and ROS for enhanced anti-inflammation therapy of 5-demethylnobiletin against psoriasis-like lesions. International journal of pharmaceutics, 645, 123373. Advance online publication.

4.张磊,王益民,王书珍,何峰,课程思政背景下中医药类课程建设的教学改革研究,美丽中国,20231月,第3期,第5卷,总第147期,47-47

5. .一种核酸样品采集用新型采集管,ZL202221277427.2张磊,何峰,王益民,吴伟

6. 一种介孔硅纳米递送载体、载药复合物、制备方法及应用,ZL202211541534.6,王益民;张磊;何峰;沈俊峰;占剑锋

7. Zhang L, He S, Li Z, Gan X, Li S, Cheng X, Yang N, Zheng F. Apolipoprotein E polymorphisms contribute to statin response in Chinese ASCVD patients with dyslipidemia. Lipids Health Dis. 2019 Jun 1;18(1):129. doi: 10.1186/s12944-019-1069-5. PMID: 31153375; PMCID: PMC6545221.

8. Zhang L, Huang Y, Gan X, He S, Cheng X, Yang N, Li S, Li Z, Zheng F. The Pharmacogenomics Side-effect of TP53/EGFR in Non-small Cell Lung Cancer Accompanied with Atorvastatin Therapy: A Functional Network Analysis. Anticancer Agents Med Chem. 2019;19(17):2060-2071. doi: 10.2174/1871520619666190712203217. PMID: 31544704.

9.张磊,郑芳. 载脂蛋白E基因分型方法学进展及其临床意义[J]. 中华检验医学杂志,2018,41(12):963-967.

10. 何思颖,杜鹏辉,张磊.血脂异常患者ApoE基因型对他汀类药物降脂疗效的影响[J].国际检验医学杂志,2019,40(11):1337-1341.

11. Li Z, Zhou Y, Yang G, He S, Qiu X, Zhang L, Deng Q, Zheng F. Using circular RNA SMARCA5 as a potential novel biomarker for hepatocellular carcinoma. Clin Chim Acta. 2019 May;492:37-44. doi: 10.1016/j.cca.2019.02.001. Epub 2019 Feb 2. PMID: 30716279.

12 Hu X, Deng Q, Li J, Chen J, Wang Z, Zhang X, Fang Z, Li H, Zhao Y, Yu P, Li W, Wang X, Li S, Zhang L, Hou T. Development and Clinical Application of a Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for SARS-CoV-2 Infection. mSphere. 2020 Aug 26;5(4):e00808-20. doi: 10.1128/mSphere.00808-20. PMID: 32848011; PMCID: PMC7449630.

13. Wang C, Luo J, Rong J, He S, Zhang L, Zheng F. Distinct prognostic roles of S100 mRNA expression in gastric cancer. Pathol Res Pract. 2019 Jan;215(1):127-136. doi: 10.1016/j.prp.2018.10.034. Epub 2018 Nov 2. PMID: 30414696.

14. Li M, Deng Q, Zhang L, He S, Rong J, Zheng F. The pretreatment lymphocyte to monocyte ratio predicts clinical outcome for patients with urological cancers: A meta-analysis. Pathol Res Pract. 2019 Jan;215(1):5-11. doi: 10.1016/j.prp.2018.10.026. Epub 2018 Oct 24. PMID: 30401580.


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